Figure 1 | Scientific Reports

Figure 1

From: The p.P888L SAP97 polymorphism increases the transient outward current (Ito,f) and abbreviates the action potential duration and the QT interval

Figure 1

p.P888L SAP97 shortens the APD. (a) Superimposed AP recorded in Sham (N = 5 mice), WT-SAP97 (N = 10) and p.P888L-SAP97 (N = 10) cardiomyocytes. (b-f) RMP (b), APA (c), and APD measured at 20% (d), 50% (e), and 90% (f) of repolarization in cardiomyocytes from the three mouse groups. *P < 0.05 vs Sham. #P < 0.05 vs SAP97 WT.

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