Figure 1 | Scientific Reports

Figure 1

From: FMR1 mRNA from full mutation alleles is associated with ABC-CFX scores in males with fragile X syndrome

Figure 1

Intergroup comparisons and relationship between FMR1 mRNA levels in PBMCs and ABC-CFX sub-scales in FM only and PM/FM mosaic males. Intergroup comparisons for (A) normalized FMR1 mRNA levels; Note: Broken parallel lines represent minimum (MIN), maximum (MAX) and median (MED) mRNA values from TD controls (n = 14), from a previous study11. Intergroup comparisons for (B) ABC-CFX Inappropriate speech scores; and (C) ABC-CFX Irritability scores between FM only and PM/FM mosaic males. (D) Relationship between normalized FMR1 mRNA levels and ABC-CFX Irritability score, with open and closed circles representing PM/FM mosaic and FM only incomplete silencing groups, respectively.

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