Figure 4 | Scientific Reports

Figure 4

From: A non-pharmacological therapeutic approach in the gut triggers distal metabolic rewiring capable of ameliorating diet-induced dysfunctions encompassed by metabolic syndrome

Figure 4

Changes in fecal microbiota induced by Policaptil Gel Retard in mice fed HFD (a) Principal coordinate analysis (PCoA) of UniFrac distances of ND and HFD control mice (n = 5–6 mice). (b) Principal coordinate analysis (PCoA) of UniFrac distances of ND and HFD Policaptil Gel Retard treated mice (n = 5–6 mice). (c) Relative abundance at phylum level in fecal community of control and Policaptil Gel Retard treated mice. (d) Representative Phyla Operational Taxonomic Unit (OTU) abundance (%) of ND control, HFD Policaptil Gel Retard, HFD control and HFD Policaptil Gel Retard mice (mean ± s.e.m, n = 5/6; ANOVA, Tukey’s post hoc). (e) Firmicutes/Bacteroidetes ratio of ND control, HFD Policaptil Gel Retard, HFD control and HFD Policaptil Gel Retard mice. (mean ± s.e.m, n = 5/6; ANOVA, Tukey’s post hoc) (f) LEfSe analysis showing differentially abundant microbiota from HFD cntrl and HFD Policaptil Gel Retard.

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