Table 3 Result of PrediXcan for FEV1/FVC ratio on KARE using lung tissue prediction model The results for PrediXcan for the top 10 genes on chromosome 6 are summarized.
From: Effect of 6p21 region on lung function is modified by smoking: a genome-wide interaction study
Gene | PrediXcan Beta | PrediXcan P value |
|---|---|---|
AGER | − 2.797 | 8.59 × 10–6 |
HLA-S | − 0.833 | 4.60 × 10–5 |
C4B | − 0.736 | 0.0003 |
MDGA1-201 | 1.312 | 0.0012 |
HLA-J | 1.065 | 0.0019 |
NKAPL | − 0.941 | 0.0042 |
HLA-DPA1 | − 0.791 | 0.0052 |
HCG4B | 0.716 | 0.0088 |
TPT1P4 | 1.522 | 0.0094 |
HLA-C | -0.549 | 0.0099 |
