Figure 2
From: Spray dried VSV-vectored vaccine is thermally stable and immunologically active in vivo
Measured log loss of VSVGFP infectivity after storage at 37 °C and < 10% RH for the positive (liquid) control, trehalose, trehalose/dextran 3:1, trehalose/dextran 1:3, mannitol/dextran 2:1 and dextran. Data are represented as mean ± SEM for three repeat samples; all data points have error bars but in some cases they are indistinguishable from the symbol itself. The results of a two-way ANOVA between excipient formulations at day 15 and 30 are shown where *P = 0.05, ***P = 0.0002, indicating that trehalose and trehalose/dextran 3:1 significantly outperform the other formulations and the liquid control at end of the storage study.
