Figure 3

D421 truncation alleviates the motor impairments induced by phospho-modified tau. Analyses of motor behaviors from flies expressing the indicated tau isoforms and lacZ control driven by GAD-Gal4. The index of each analysis includes distance (a), speed (b), and wobbling time ratio (c), should refer to Methods for detail. At least 20 flies from three different ages (1-day, 6-day, 10-day) of each genotype were tested. Values shown represent mean ± SE. *p < 0.05, ***p < 0.001 (two-way ANOVA with LSD post hoc tests).