Figure 1
From: Post-mortem ventricular cerebrospinal fluid cell-free-mtDNA in neurodegenerative disease
Comparison of vCSF-cfmtDNA levels in NDDs and matched controls. Boxplots of vCSF-cfmtDNA levels in NDD, showing vCSF-cfmtDNA levels in (a) each NDD and matched controls, (b) NDDs grouped and stratified by tau-Braak Stage and (c) NDDs stratified by dementia status. Where AD = Alzheimer’s Disease, DLB = dementia with Lewy bodies, PSP = progressive supranuclear palsy, MND = motor neuron disease, FTD/VD = frontotemporal lobar dementia/vascular dementia and PD = Parkinson’s disease. Boxes show median (thick line), 25th and 75th percentile and whiskers show 95% confidence interval. *indicates significance at p < 0.05 using ANOVA with Dunnett’s post-hoc test (a, with control as reference & c, with I/II as reference) and Student’s TTEST of yes versus no (b).
