Figure 4
From: Lactobacillus reuteri DSM 17938 and ATCC PTA 5289 ameliorates chemotherapy-induced oral mucositis
Effects of L. reuteri (LR) mixture on 5-FU-induced oxidative stress. Immunohistochemical analysis of the expression of (A,B) 8-OH-dG, (D,E) 4-HNE and (G,H) Nrf-2 in the oral mucosa of (A,D,G) 5-FU/water and (B,E,H) 5-FU/LR treated mice. Arrow indicates positively stained cells. Quantitative analysis of number of positively stained (C) 8-OH-dG, (F) 4-HNE, (I) Nrf-2 cells. (J) RT-qPCR analysis of antioxidant gene expression in the oral mucosa. ***p < 0.001.
