Table 1 Patients background.
 | Tocilizumab | Etanercept | p-value | ||
---|---|---|---|---|---|
First | Second | First | Second | ||
Patient number | 42 | 34 | 103 | 17 | Â |
Age | 57.0 ± 15.9 | 57.9 ± 17.9 | 52.3 ± 13.0 | 51.9 ± 6.7 | 0.141 |
RA duration | 1.8 ± 1.7 | 2.0 ± 1.9 | 2.2 ± 1.3 | 2.1 ± 1.2 | 0.266 |
Steinbrocker stage | 2.5 ± 0.6 | 2.6 ± 1.1 | 2.4 ± 0.8 | 2.4 ± 0.9 | 0.642 |
Steinbrocker class | 2.3 ± 0.9 | 2.0 ± 0.8 | 1.7 ± 0.6 | 1.4 ± 0.5 | 0.074 |
MTX dose (mg/week) | 4.9 ± 3.9 | 3.1 ± 3.2 | 5.5 ± 4.4 | 6.2 ± 5.4 | 0.089 |
glucocorticoid dose (mg/day) | 1.5 ± 3.8 | 3.7 ± 4.0 | 2.7 ± 2.8 | 3.9 ± 3.0 | 0.065 |
Total sharp score | 71.4 ± 72.9 | 87.8 ± 91.4 | 45.0 ± 46.4 | 53.5 ± 63.6 | 0.037 |
Sharp score (erosion) | 34.5 ± 40.1 | 42.3 ± 53.8 | 28.6 ± 34.9 | 25.9 ± 28.6 | 0.057 |
Sharp score (joint narrow) | 37.6 ± 36.3 | 43.6 ± 44.3 | 25 ± 29.7 | 19.1 ± 18.6 | 0.022 |
Total sharp score/year | 37.7 ± 45.8 | 50.6 ± 45.0 | 25.2 ± 27.1 | 22.4 ± 18.3 | 0.001 |
Sharp score (erosion)/year | 21.2 ± 23.7 | 23.8 ± 24.0 | 13.1 ± 14.5 | 12.5 ± 10.9 | 0.057 |
Sharp score (joint narrow)/year | 19.7 ± 21.8 | 26.8 ± 24.8 | 12.0 ± 14.0 | 9.8 ± 8.1 | 0.001 |