Figure 6
From: Gfi1 upregulates c-Myc expression and promotes c-Myc-driven cell proliferation
Gfi1 knockdown and deficiency downregulate c-Myc expression. (A) The expression of c-Myc protein (upper panels) and mRNA (lower panels) was examined in U937 and HL60 cells expressing the scrambled shRNA (Ctr) or shRNAs against Gfi1 (#65 and #68). (B) c-Myc protein and mRNA expression in Lin- BM cells from Gfi1+/+ and Gfi1-/- mice was examined. Data are shown as mean ± SD. Full-length blots are presented in Supplementary Fig. 11.
