Table 1 Baseline characteristics for mildly obese nondiabetic subjects compared to morbidly obese subjects.
|  | Mild obesity (n = 15) | Morbid obesity (n = 29) | p value |
|---|---|---|---|
Demographic characteristics | |||
Age (years) | 63.1 ± 5.4 | 47.1 ± 11.0 | < 0.001 |
Female sex, n (%) | 1 (2.3) | 27 (61.4) | < 0.001 |
Diabetes mellitus, n (%) | 0 (0%) | 13 (45%) | Â |
Anthropometric and blood pressure | |||
Weight (kg) | 89.3 ± 13.6 | 145.9 ± 21.4 | < 0.001 |
Weight (lb) | 196.9 ± 30.1 | 321.5 ± 47.1 | < 0.001 |
Waist circumference (cm) | 106.4 ± 7.7 | 144.2 ± 12.4 | < 0.001 |
Waist circumference (inches) | 41.9 ± 3.0 | 56.8 ± 4.9 | < 0.001 |
BMI (kg/m2) | 30.5 ± 2.7 | 53.0 ± 7.3 | < 0.001 |
Systolic BP (mm Hg) | 125.6 ± 16.1 | 128.5 ± 12.7 | 0.52 |
Diastolic BP (mm Hg) | 74.2 ± 9.9 | 76.0 ± 8.8 | 0.55 |
Biochemical profile | |||
Glucose (mg/dl) | 94.0 ± 8.9 | 111.7 ± 35.5 | 0.07 |
HbA1c (%) | 5.8 ± 0.3 | 6.3 ± 1.1 | 0.07 |
Insulin (mIU/ml) | 13.3 ± 8.1 | 26.8 ± 14.9 | 0.002 |
AST (IU/l) | 22.1 ± 7.0 | 28.8 ± 19.1 | 0.20 |
ALT (IU/l) | 25.8 ± 11.8 | 30.1 ± 17.1 | 0.38 |
WBC (109 cells/l) | 6.07 ± 1.53 | 8.51 ± 2.86 | 0.004 |
Platelet count (cells/µl) | 167.2 ± 40.2 | 253.14 ± 86.65 | 0.001 |
Lipids (mg/dl) | |||
Total cholesterol | 154.5 ± 30.7 | 185.3 ± 41.5 | 0.15 |
Triglycerides, median [IQR] | 125.0 [71.0,188.0] | 162.0 [148.0,196.5] | 0.028 |
HDL-C | 46.3 ± 12.3 | 43.4 ± 11.4 | 0.44 |
LDL-C | 80.1 ± 23.2 | 105.1 ± 32.2 |  < 0.001 |
TC/HDL ratio | 3.6 ± 1.4 | 4.4 ± 1.1 | 0.028 |
