Figure 3

Identification of 71 hub genes through machine learning and bioinformatics in selected modules. (A) Genes and gene interactions by topological overlap matrix in WGCNA. The color red represents gene–gene interactions. (B) ROC of single gene for T/M stages. (C) RF of single gene for T/M stages. (D) Protein-protein interaction network of hub genes. WGCNA, weighted gene co-expression network analysis; RF, random forest; ROC, receiver operating characteristic curve.