Figure 4

Dynamic redistribution of myosin II in stress fibers (SFs). (A) Distinct distribution of myosin II in unstretched cells and after applying cyclic stretch (CS) for 2 h (upper panel). Redistribution of myosin II post-CS release (lower panel). Scale bars: 100 µm. (B–D) Remodeling of myosin II is quantified by the spacing between myosin bands along with SFs in cyclically stretched cells at 5% (B), 10% (C), and 15% (D) strains (n = 3). Error bars indicate mean ± SD. *p < 0.01; one-way analysis of variance (ANOVA).