Table 2 Univariate and multivariate linear regression analyses of blood NfL level and age, sex, BMI and serum creatinine.

From: Renal function is associated with blood neurofilament light chain level in older adults

Variable

Univariate analysis

Multivariate analysis

Standardized β

p-value

Standardized β

p-value

HC group (n = 43, serum NfL)

Age

0.110

0.48

0.134

0.33

Sex [M]

0.091

0.56

− 0.212

0.17

BMI

− 0.040

0.80

− 0.238

0.10

Serum creatinine

0.498

0.0007

0.660

0.0001

DM group (n = 188, plasma NfL)

Age

0.400

< 0.0001

0.320

< 0.0001

Sex [M]

0.121

0.10

− 0.236

0.0001

BMI

− 0.231

0.0014

− 0.211

< 0.0001

Serum creatinine

0.560

< 0.0001

0.656

< 0.0001

  1. See also supplementary Figs. 1 and 2.
  2. BMI body mass index; NfL neurofilament light chain.
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