Figure 1
From: Microbiota attenuates chicken transmission-exacerbated campylobacteriosis in Il10−/− mice

Chicken-transmitted C. jejuni (Cj-P1) induced more severe colitis compared to AR101 (Cj-P0). Cohorts of 5–9 SPF Il10−/− mice were orally gavaged daily with clindamycin for 7 days. The mice were then gavaged with a single dose of 109 CFU/mouse C. jejuni of Cj-P0 (5 mice) and Cj-P1 (9 mice) and were euthanized 8 days post-infection. (A) H&E staining showing representative intestinal histology of C. jejuni-induced colitis in Il10−/− mice. (B) Quantification of histological intestinal damage score. *, P < 0.05. Data represent means ± SEM. Scale bar is 200 μm. Results are representative of 3 independent experiments.