Table 1 Baseline demographic and clinical characteristics.
Characteristics | Sleep apnea (+) DM (+) (n = 295) | Sleep apnea (+) DM (─) (n = 218) | Sleep apnea (─) DM (+) (n = 278) | Sleep apnea (─) DM (─) (n = 216) | p value |
---|---|---|---|---|---|
Age, median (IQR), years | 62 (57–67) | 62 (56–68) | 62 (56–68) | 60 (56–66.75) | 0.341 |
Male sex, n (%) | 245 (83.1) | 197 (90.4) | 231 (83.1) | 198 (91.7) | 0.004 |
Ethnicity, n (%) | |||||
Chinese | 191 (64.7) | 147 (67.4) | 158 (56.8) | 156 (72.2) | 0.017 |
Malay | 52 (17.6) | 41 (18.8) | 63 (22.7) | 38 (17.6) | Â |
Indian | 34 (11.5) | 16 (7.3) | 42 (15.1) | 15 (6.9) | Â |
Others | 18 (6.1) | 14 (6.4) | 15 (5.4) | 7 (3.2) | Â |
Clinical measurements | |||||
Systolic blood pressure, mean (SD), mm Hg | 126 (20) | 126 (18) | 127 (19) | 125 (19) | 0.803 |
Diastolic blood pressure, mean (SD), mm Hg | 71 (11) | 72 (10) | 70 (11) | 72 (11) | 0.116 |
Body mass index, mean (SD), kg/m2 | 26.4 (4.2) | 26.2 (4.4) | 24.3 (3.7) | 23.9 (3.4) | < 0.001 |
Neck circumference, mean (SD), cm | 39.4 (3.4) | 39.1 (3.5) | 38.0 (3.1) | 37.7 (3.0) | < 0.001 |
Waist circumference, mean (SD), cm | 96.8 (10.4) | 95.4 (11.7) | 91.0 (9.7) | 89.2 (9.2) | < 0.001 |
Cardiovascular risk factors, n (%) | |||||
Smoking | 73 (24.7) | 66 (30.3) | 82 (29.5) | 73 (33.8) | 0.028 |
Hyperlipidaemia | 258 (87.5) | 159 (72.9) | 239 (86.0) | 162 (75.0) | < 0.001 |
Hypertension | 255 (86.4) | 149 (68.3) | 219 (78.8) | 130 (60.2) | < 0.001 |
Insulin dependence | 148 (50.1) | – | 133 (47.8) | – | 0.233 |
Concomitant conditions, n (%) | |||||
Previous myocardial infarction | 145 (49.2) | 94 (43.1) | 123 (44.2) | 98 (45.4) | 0.522 |
Previous percutaneous coronary intervention | 78 (26.4) | 41 (18.1) | 60 (21.6) | 41 (19.0) | 0.118 |
Previous coronary artery bypass surgery | 0 (0.0) | 0 (0.0) | 1 (0.4) | 1 (0.5) | 0.543 |
Stroke/transient ischemic attack | 33 (11.2) | 28 (12.8) | 40 (14.4) | 17 (7.9) | 0.148 |
Chronic kidney disease | 74 (25.1) | 28 (12.8) | 49 (17.6) | 14 (6.5) | < 0.001 |
Chronic kidney disease on dialysis | 22 (7.5) | 6 (2.8) | 8 (2.9) | 0 (0.0) | < 0.001 |
Pre-existing atrial fibrillation | 13 (4.4) | 11 (5.0) | 15 (5.4) | 8 (3.7) | 0.826 |
Pacemaker in-situ | 1 (0.3) | 1 (0.5) | 0 (0.0) | 1 (0.5) | 0.745 |
Implantable cardioverter defibrillator in-situ | 3 (1.0) | 0 (0.0) | 1 (0.4) | 0 (0.0) | 0.203 |