Figure 3
From: Evolutionary design of optimal surface topographies for biomaterials
The flow of genetic perturbations. (A) Schematic representation of the genetic perturbation flow. (B) Schematic representation of surface numbers in every step of genetic perturbation. (C) Examples of control surfaces. (D) Different sizes of the ALP hit surface. (E) The flow of genetic perturbations with the second generation of the GTopoChip1. Every bubble corresponds to a single function or parameter that belongs to step specified on X-axis. The size of the bubble represents the number of surfaces that were generated with that particular function or parameter. (F) Example of surface generation: after parental crossover one child has 3 consecutive mutation steps. Yellow and blue colours correspond to the parents, green colour represents inserted elements of the design, and white outline represents removed elements of the design.
