Figure 1
From: Differences of the tumour cell glycocalyx affect binding of capsaicin-loaded chitosan nanocapsules
Genetic alterations in glycocalyx-related genes. (a,b) Screening of public exome sequencing data indicate somatic mutations and copy number alterations (CNAs) in tissues of melanoma (mela.) and bladder cancer (bladder). (a) Shown are the percentages of patients with genetic alterations in the proteoglycans syndecan 1 (SDC1), SDC2, SDC3 and SDC4, the heparan sulphate degrading heparanase (HPSE), exostosin glycosyltransferase 1 (EXT1) and EXT2. (b) Shown are the percentages of patients with genetic alterations in hyaluronidase 1 (HYAL1) and HYAL2 and hyaluronan synthases (HAS1), HAS2 and HAS3.
