Figure 1 | Scientific Reports

Figure 1

From: Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion

Figure 1

Effects of AT1a receptor loss on prevention of AKI to CKD transition at 70 days postischemia. The right kidneys received unilateral ischemic reperfusion (IR) and the left kidneys were contralateral (non-IR kidneys). (a) Time-related changes in systolic blood pressure from 7 days before IR surgery to 70 days postischemia. (b) IR kidney weight shown as the fold-increase or fold-decrease compared with the non-IR kidneys. (c,d) Cross-sectional area of the IR kidney cut in transverse plane at the hilum of the kidney (c), which was evaluated as the fold-increase or fold-decrease compared with the non-IR kidney (d). Values are means ± SE. *P < 0.05 vs. AT1a+/+ mice on the same day, #P < 0.05 vs. the AT1a+/+  + Hyd mice on the same day.

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