Figure 6 | Scientific Reports

Figure 6

From: Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion

Figure 6

Gene expression analysis for renal fibrosis and inflammatory cytokines at 14 and 28 days postischemia. (a–f) Gene expressions of α-1 collagen type I (a), α-1 collagen type III (b), TGF-β (c), MCP-1 (d), IL-18 (e), and IL-1β (f) in the IR kidneys. The graphs show the fold-increase or -decease in each gene expression in the IR kidney compared with that of the sham. Values are means ± SE. *P < 0.05 vs. AT1a+/+ mice on the same day, §P < 0.05 vs. AT1a+/+ mice at 14 days postischemia, †P < 0.05 vs. AT1a−/− mice at 14 days postischemia.

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