Figure 7
Artemether increased mitochondrial mass and improved mitochondrial function. (a–e) Western blot images and quantitative analysis of VDAC, TOM20, COX IV, and Tfam in renal tissue of various groups. n = 4 per group. (f) Mitochondrial H2O2 release rate in each group after artemether treatment for 2 weeks. n = 6 per group. (g–l) Bar graphs indicating the quantification of mitochondrial DNA copy number (determined by qPCR for ND1, cytochrome b, and 16S rRNA against β-actin and HK-2) in each group. n = 6 per group. *P < 0.05 and **P < 0.01 versus control; #P < 0.05, ##P < 0.01 and ###P < 0.001 versus AN.
