Figure 2 | Scientific Reports

Figure 2

From: Differential expression and correlation analysis of miRNA–mRNA profiles in swine testicular cells infected with porcine epidemic diarrhea virus

Figure 2

mRNAs expression profiles in PEDV-infected ST cells. (a) The bar graph shows the number of DE mRNAs in each one of the three comparison groups, red represents the amount of up-regulated DE mRNAs, green represents the count of down-regulated DE mRNAs (p-value < 0.05). (b) GO analysis of the DE mRNAs in PEDV infection ST. The three panels show the GO enrichment analysis of each of the top 30 significantly most DE mRNAs from the three comparison groups (YN15 vs Control, YN144 vs Control, and YN15 vs YN144), respectively. (c) KEGG analysis of the DE mRNAs in ST cells infected with PEDV. The three panels show the KEGG enrichment analysis of each of the top 20 significantly most DE mRNAs between YN15, YN144 and control groups, respectively. (d) Results of relative quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) analysis (alongside RNA-seq analysis) of ATF3, CRAMP, NKTR, RND1, SMAGP and TNFSF10 in YN15- and YN144-infected ST cells, respectively. The relative expression of each mRNA was calculated using the 2-ΔΔCt method. The data are presented as mean ± SEM from three independent experiments.

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