Figure 6
From: Cholesterol as a modulator of cannabinoid receptor CB2 signaling
Effect of treatment with MβCD/Chol of E. coli membranes on activation of CB2 by synthetic ligands. (a) Membranes expressing CB2 were treated with 20 mM MβCD/Chol for 1 h at 4 °C, washed with PBS, and the activation of CB2 in the presence of ligands determined by GEF; (b) control, untreated E. coli membranes expressing CB2. Each data point represents an average of four independent measurements (n = 4) with standard deviation indicated by vertical bars.
