Figure 4 | Scientific Reports

Figure 4

From: Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes

Figure 4

Reactivity of human sera against C. albicans mannan and BSTO. Reactivity against C. albicans mannan (a) as detected by ELISA (Platelia Candida Ab test), and against BST-3β-Man (b), as detected by multi-analyte profiling (MAP) analysis. Human sera consisted of sera from healthy controls (blood donors presenting no disease), and ICU patients either not-infected or infected with C. albicans. Anti-C. albicans mannan antibody response is shown for infected patients according to antigenemia status (negative: open symbols; positive: closed symbols) (b). The correlation between anti-mannan and 2α-Man, 2β-Man, 3β-Man antibodies is shown in (c, d, e) respectively. The values of Spearman rank correlation coefficients for the different BSTOs are given in f.

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