Figure 3 | Scientific Reports

Figure 3

From: Demyelination and remyelination detected in an alternative cuprizone mouse model of multiple sclerosis with 7.0 T multiparameter magnetic resonance imaging

Figure 3

Trends and comparisons of MRI metrics of time points of mice model. (a) the T2-nor value was increased during the demyelination process and decreased during the remyelination process; (b) the Φ value of SWI has remained slight fluctuated during the whole process; (c) FA value was decreased during the demyelination process, reached the valley at the 10w group, then increased in the 13w group; (d) MD value was decreased slightly to the valley at 3w group then increased continuously till reached the peak at the 10w group, finally following decreased at 13w group; (e) RD value was increased till reached the peak at the 10w group, then following decreased at 13w group; (f) the trend polyline of the AD value owned the valley at the 3w group and the peak at the 10w group. Compared with the 0w group, statistically differences are *p < 0.05, **p < 0.01, ***p < 0.001.

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