Table 2 Association of clinical and pathological characteristics with GPNMB expression in 98 patients with TNBC.
Characteristics | Number of patients (n = 98) | GPNMB expression | P-value | |
|---|---|---|---|---|
Low (n = 44) | High (n = 54) | |||
Age | ||||
≤ 60 | 60 | 24 (54.5) | 36 (66.7) | 0.221 |
> 60 | 38 | 20 (45.5) | 18 (33.3) | |
Tumor stage | ||||
Tis | 1 | 0 (0) | 1 (1.9) | 0.530 |
T1 | 31 | 13 (29.5) | 18 (33.3) | |
T2 | 59 | 28 (63.6) | 31 (57.4) | |
T3 | 2 | 0 (0) | 2 (3.7) | |
T4 | 5 | 3 (6.8) | 2 (3.7) | |
Nodal status | ||||
N0 | 56 | 27 (61.4) | 29 (53.7) | 0.558 |
N1 | 22 | 8 (18.2) | 14 (25.9) | |
N2 | 7 | 2 (4.5) | 5 (9.3) | |
N3 | 13 | 7 (15.9) | 6 (11.1) | |
TNM stage | ||||
DCIS + I + II | 75 | 33 (75.0) | 42 (77.8) | 0.813 |
III | 23 | 11 (25.0) | 11 (22.2) | |
Grade | ||||
1 + 2 | 36 | 8 (18.2) | 28 (51.9) | 0.001 |
3 | 62 | 36 (81.8) | 26 (48.1) | |
Lymphovascular invasion | ||||
Absent | 76 | 31 (72.1) | 45 (83.3) | 0.182 |
Present | 21 | 12 (27.9) | 9 (16.7) | |
NAa | 1 | |||
Tumor necrosis | ||||
Absent | 41 | 20 (45.5) | 21 (38.9) | 0.512 |
Present | 57 | 24 (54.5) | 33 (61.1) | |
