Table 3 Univariate and multivariate Cox analysis of factors associated with recurrence free survival (RFS) and distant metastasis-free survival (DMFS) in patients with TNBC.
Univariate RFS analysis | Multivariate RFS analysis | |||
|---|---|---|---|---|
Hazard ratio (95% CI) | P | Hazard ratio (95%CI) | P | |
GPNMB H-score (> 75.5 vs. ≤ 75.5) | 2.57 (1.36–5.84) | 0.011 | 3.22 (1.36–7.61) | 0.008 |
Lymphovascular invasion (present vs. absent) | 3.45 (1.65–7.19) | < 0.001 | 2.16 (0.78–5.97) | 0.136 |
Grade (3 vs. 2–1) | 0.56 (0.27–1.17) | 0.119 | – | – |
Stage (III vs. II–I–DCIS) | 4.13 (1.99–8.59) | < 0.001 | 4.58 (2.19–9.56) | < 0.001 |
Univariate DMFS analysis | Multivariate DMFS analysis | |||
|---|---|---|---|---|
Hazard ratio (95% CI) | P | Hazard ratio (95%CI) | P | |
GPNMB H-score (> 75.5 vs. ≤ 75.5) | 2.51 (1.15–5.48) | 0.020 | 3.08 (1.22–7.74) | 0.017 |
Lymphovascular invasion (present vs. absent) | 2.52 (1.26–5.02) | 0.006 | 1.88 (0.62–5.67) | 0.259 |
Grade (3 vs. 2–1) | 0.64 (0.32–1.24) | 0.183 | – | – |
Stage (III vs. II–I–DCIS) | 3.72 (1.71–8.07) | 0.001 | 4.02 (1.85–8.75) | < 0.001 |
