Figure 2 | Scientific Reports

Figure 2

From: Cross-sectional imaging of intestinal barrier dysfunction by confocal laser endomicroscopy can identify patients with food allergy in vivo with high sensitivity

Figure 2

Barrier dysfunction in the terminal ileum in patients with and without Food Allergy. Overall, 26 out of 27 patients (= 96%) in the FA group exhibited barrier dysfunction in the terminal ileum under functional imaging with pCLE. In detail, 10 patients out of 27 patients (= 37%) exhibited a structural barrier dysfunction (Watson III) and 16 patients out of 27 patients (= 59.3%) had a functional barrier defect (Watson II). In the non-FA group, 11 out of 33 patients (= 33%) had barrier dysfunction, all of which were functional barrier defects. Differences in barrier dysfunction between patients with and without FA were statistically significant (p < 0.0001). Middle panel: Representative images of the different grades of barrier dysfunction on pCLE; from bottom to top: Watson I, Watson II, Watson III.

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