Figure 4

Graphs are illustrating the correlations between the percentage change in sensitization and the expression frequency of nerve fibers within connective tissue. The correlation between the percentage change (from day 0 to day 10) of pressure pain threshold (PPT) and the change (from day 0 to day 10) in the frequency of positive fibers within the connective tissue expressing (A,B) NMDA-receptor2B alone and (C,D) NMDA-receptor2B in combination with nerve growth factor (NGF) for women (n = 15) and age-matched men (n = 15).