Figure 5

Graphs illustrating the correlations between the level of sensitization and frequency of nerve fibers co-expressing substance P and NMDA-receptor2B within connective tissue. The correlation between the percentage change of pressure pain threshold (PPT), chewing pain and temporal summation pain (from baseline to 5Â min after glutamate injection) and the frequency of nerve-fibers co-expressing substance P and NMDA-receptor2B on day 0 in 15 healthy women and 15 age-matched men. (A,B) PPT in women and men, respectively. (C,D) Chewing pain (functional test) in women and men, respectively. (E,F) temporal summation pain in women and men, respectively.