Figure 2
From: The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway

The proliferation and migration of HUVECs were significantly inhibited by COL-4A1. (A) HUVECs were treated with or without COL-4A1 and with or without TNF-α before CCK-8 proliferation assays. (B–E) Wound-healing and Transwell assays were used to detect the ability of in the cells in each group to migrate. All images were captured at ×200 magnification. (*P < 0.05, **P < 0.01, ***P < 0.001).