Figure 3
From: The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway
Effects of COL-4A1 on tube formation, ROS levels, and adhesive ability. (A) Qualitative and quantitative analyses of tube formation by HUVECs. Tube formation was eliminated in the COL-4A1-treated cells (with or without TNF-α). (B) COl-4A1 obviously increased the level of ROS in each group. (C) COl-4A1 increased the adhesive ability of each group. All images were captured at ×100 magnification. (*P < 0.05, **P < 0.01, ***P < 0.001).
