Figure 2

Best-fitting regression models to identify relationships between changes in AL and time in the treated and untreated eyes during the observation (n = 32) (a) and treatment (n = 40) (b) periods. (a) Best-fitting models of the changes in AL with time during the observation period in the treated and untreated eyes were both linear and produced high correlations (R² = 0.647 and 0.639, respectively). The linear formulas are y = 0.0242x – 0.0038 for the treated eyes and y = 0.0176x – 0.0012 for the untreated eyes. (b) Best-fitting models of the changes in AL with time during the treatment period in the treated and untreated eyes were quadratic with a concave function (R² = 0.068) and linear (R² = 0.422), respectively. The green triangle indicates the turning point (x = 4.8 months) when the slope of the changes in AL became positive in the treated eyes. The quadratic formula is y = 0.0008x² − 0.0076x − 0.0241 for the treated eyes and the linear formula is y = 0.0236x + 0.0085 for the untreated eyes.