Table 1 Aspergillus fumigatus strains used in this experiment and their drug susceptibility profiles against itraconazole and voriconazole.

IFM63432^a

Clinic

TR₄₆²/Y121F/T289A

4

 > 8

BE1-2

Environment (bulb)^b

TR₄₆²/Y121F/T289A

2

 > 8

BE1-4

Environment (bulb)

TR₄₆²/Y121F/S363P/I364V/G448S

2

 > 8

BE 3-5

environment (bulb

TR₄₆²/Y121F/T289A

2

 > 8

BE 3-6

Environment (bulb)

TR₄₆²/Y121F/T289A

2

 > 8

BE 1-1

Environment (bulb)

TR₄₆³/Y121F/M172I/T289A/G448S

2

 > 8

W1-4

Environment (bulb)

TR₄₆³/Y121F/M172I/T289A/G448S

2

 > 8

W2-12-1

Environment (bulb)

TR₄₆³/Y121F/M172I/T289A/G448S

2

 > 8

IFM64460

Clinic

TR₃₄/L98H

 > 8

 > 8

IFM64733

Environment

TR₃₄/L98H

 > 8

 > 8

3-1-B

Environment (bulb)

TR₃₄/L98H/T289A/I364V/G448S

2

 > 8

IFM62918^c

Clinic

Wild

0.5

1

IFM62799

Clinic

Wild

0.5

1

IFM60516

Clinic

Wild

1

1

IFM58402

Clinic

Wild

0.5

0.5

IFM51977

Clinic

Wild

0.25

0.25

IFM60065

Clinic

Wild

1

0.5

IFM61960

Clinic

Wild

0.5

0.5

IFM51748

Clinic

Wild

0.125

0.125

IFM63666

Clinic

Wild

1

2

IFM62520

Clinic

Wild

1

0.5

IFM50999

Clinic

Wild

0.5

0.5

IFM50268

Clinic

Wild

0.25

0.125

IFM55548

Clinic

Wild

0.25

0.25

IFM63311

Clinic

Wild

1

0.5

IFM63355

Clinic

Wild

2

2

IFM60901

Clinic

Wild

0.5

0.5

IFM62674

Clinic

Wild

1

2

IFM62709

Clinic

Wild

0.5

0.5

IFM52659

Clinic

Wild

1

1

IFM57130

Clinic

Wild

0.25

0.125

IFM60814

Clinic

Wild

0.5

0.5

IFM49435

Clinic

Wild

0.25

0.25

IFM61572

Clinic

Wild

0.5

0.5

IFM50669

Clinic

Wild

0.5

0.25

IFM59832

Clinic

Wild

0.5

0.5

IFM55044

Clinic

Wild

0.25

0.25

IFM47670

Clinic

Wild

0.5

0.5

IFM51978

Clinic

Wild

0.5

0.25

IFM58328

Clinic

Wild

0.5

0.5

IFM60369

Clinic

Wild

0.5

0.5