Table 4 Hazard ratio of IRF associated to prediabetes and type of prediabetes using different models.

From: Heterogeneity in the association between prediabetes categories and reduction on glomerular filtration rate in a 5-year follow-up

 

Model 1

Model 2

Model 3

Model 4

 

HR

95%CI

HR

95%CI

HR

95%CI

HR

95%CI

Normoglycemia

Ref

       

Prediabetes

0.89

(0.64–1.24)

0.90

(0.65–1.25)

0.76

(0. 54–1.07)

0.76

(0. 54–1.07)

HbA1c 5.7–6.4%

0.71

(0.43–1.20)

0.72

(0.43–1.21)

0.68

(0.40–1.14)

0.68

(0.40–1.15)

FPG 100–125 mg/dL

1.24

(0.76–2.03)

1.28

(0.78–2.11)

1.10

(0.66–1.82)

1.12

(0.68–1.85)

HbA1c: 5.7–6.4% & FPG 100–125 mg/dL

0.87

(0.59–1.27)

0.87

(0.59–1.28)

0.69

(0.46–1.03)

0.68

(0.45–1.02)

  1. Model 1 (sex- and age-adjusted).
  2. Model 2 (Model 1 plus adjusted by lifestyle variables (i.e. smoking status, regular physical activity, high-risk alcohol consumption, adherence Mediterranean diet (MedDiet) score, and daily consumption of fruit or vegetables).
  3. Model 3 (Model 2 plus adjusted by metabolic risk factors (i.e. Waist circumference, BMI, hypertension, total cholesterol, HDL-cholesterol, triglycerides s).
  4. Model 4 (Model 3 plus adjusted by use of ACEIs or ARBs).