Figure 8 | Scientific Reports

Figure 8

From: Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment

Figure 8

Immunofluorescence staining of FRβ-expressing tumor-associated macrophage population following treatment with AGF94. Slides were stained with FRβ (Genetex) with Alexa Fluor 488 secondary antibody and pan-Macrophage, F4/80, conjugated to APC-R700 (BD Biosciences). Images were acquired by confocal microscopy. Immunofluorescence staining is shown for representative tumor sections from control mice and mice treated with 4 doses of AGF94. The scale is 20 µm.

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