Figure 4
From: Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI
Representative tumor findings in mutant mice. At the third observation time point, a female mutant was found to have a large spleen (a). In (b) tumorous tissue was observed in the axillary region of an 8-month-old female. In (c) cancerous tissue is located in the pelvic region of a one-year-old female. (d–i) panel showing 2D fs-RARE data, starting at eight months of age, tracking cancer development in two mutant individuals over a six-month period. A mammary tumor is shown in (d–f), and a splenic hemangioma (tumor indicated by white arrow) is shown in (g–i) with the corresponding histologic finding as an insert in (i).
