Table 2 Overview of the applied MR protocols.

From: Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI

Protocol

TR (ms)

TE (ms)

Flip angle

Rare factor

Bandwidth (kHz)

Averages

FOV (mm2)

Spatial resolution (mm3)

MR morphometry

2D RARE

2475

12.6

90°/180°

4

81.5

4

35 × 38

0.18 × 0.19 × 0.25

3D FISP

5

1.4

15°

–

119.05

4

35 × 38

0.22 × 0.24 × 0.25

Protocol

TR (ms)

TE (ms)

Flip angle

Images

TI (ms)

Bandwidth (kHz)

Averages

FOV (mm2)

Spatial resolution (mm3)

MR relaxometry

T1: IR-FISP

10,500

2.65

180°/10°

7

57/Δ480

62.5

2

30 × 30

0.19 × 0.19 × 1

T2: MSME

2000

6

90°/180°

14

–

98.7

1

30 × 30

0.19 × 0.19 × 0.75

  1. The MR morphometry comprised a high resolution 2D rapid acquisition with relaxation enhancement (RARE) and a 3D fast imaging with steady-state precession (FISP) sequence. The T1 relaxation time was measured based on a Look-Locker approach sampling the T1 dynamic using an inversion recovery FISP (IR-FISP) technique. The transversal relaxation time T2 was derived from a multi-slice multi-echo (MSME) protocol.
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