Figure 1
From: A resource for integrated genomic analysis of the human liver
Liver RNA-Seq eQTLs. (A) SNP-level analysis of the UNC liver data, showing minimum association p values for local (cis) SNPs for each gene. (B) Gene level (eGene) results for the resource. (C) Transcriptome-wide association plot, showing SNP genomic position on the x-axis, and transcription start site for the gene on the y-axis. Association P values are color-coded according to two levels of stringency as shown. (D) Normalized expression vs. genotype for a strongly associated gene and SNP rs2910788, expressed as number of minor alleles (association p < 10–20). (E) P values for an allelic fold-change measure show correspondence of gene-level results for GTEx liver vs. the UNC liver data (Spearman ρ = 0.30, p < 0.001).
