Figure 1
From: Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development
Expression of Fat cadherins in developing spinal cord. (A) Expression pattern of Fat3 in mouse embryonic spinal cord by ISH (cervical level). Fat3 is mainly expressed in the ventricular zone and then remained in the mantle zone (MZ) of spinal cord from E10.5–12.5. (B) Fat3 protein was detected in the MZ barely at E11.5 by immunohistochemistry (IHC). Sox2 staining shows the neural stem cells and TuJ staining represents differentiated neuronal area. (C) Expression patterns of Fat3, Fat1 and Fat4 in chick spinal cord by ISH. Dotted outlines indicate the border of the spinal cord. Scale bars: 100 μm.
