Table 1 Baseline characteristics and associations with hand dexterity.

Demographics

   Male sex, n (%)

180 (58)

0.29 (0.18 to 0.40)

 < 0.001

–

–

   Age, years

56 ± 13

0.44 (0.34 to 0.54)

 < 0.001

–

–

Educational level, n (%)

   Low

114 (38)

Reference

n/a

Reference

n/a

   Medium

114 (38)

− 0.21 (− 0.33 to − 0.08)

0.001

− 0.09 (− 0.20 to 0.02)

0.1

   High

304 (25)

− 0.20 (− 0.33 to − 0.08)

0.001

− 0.18 (− 0.29 to − 0.07)

 < 0.001

Caucasian, n (%)

297 (4)

− 0.08 (− 0.19 to 0.04)

0.2

− 0.08 (− 0.17 to 0.02)

0.1

Body mass index, kg/m²

28 ± 5

0.07 (− 0.04 to 0.18)

0.2

0.11 (0.01 to 0.21)

0.025

Primary kidney disease, n (%)

   Unknown

46 (15)

Reference

n/a

Reference

n/a

   Inflammatory disease

103 (33)

0.02 (− 0.14 to 0.18)

0.8

0.03 (− 0.11 to 0.16)

0.7

   Congenital and hereditary kidney disease

83 (27)

− 0.13 (− 0.28 to 0.03)

0.1

− 0.13 (− 0.26 to 0.01)

0.062

   Kidney vascular disease, excl. vasculitis

27 (9)

0.02 (− 0.11 to 0.15)

0.8

− 0.02 (− 0.13 to 0.10)

0.8

   Diabetic kidney disease

20 (7)

0.17 (0.04 to 0.30)

0.010

0.17 (0.06 to 0.28)

0.003

   Other

30 (10)

− 0.02 (− 0.15 to 0.12)

0.8

− 0.03 (− 0.14 to 0.09)

0.6

Diabetes, n (%)

86 (28)

0.22 (0.11 to 0.33)

 < 0.001

0.17 (0.08 to 0.27)

 < 0.001

Anemia, n (%)

96 (31)

0.08 (− 0.03 to 0.19)

0.2

0.11 (0.01 to 0.20)

0.032

Lifestyle parameters

Alcohol intake, units/week, n (%)

   None

109 (37)

Reference

n/a

Reference

n/a

    < 7 units/week

118 (41)

− 0.09 (− 0.22 to 0.04)

0.2

− 0.07 (− 0.19 to 0.04)

0.2

    ≥ 7 units/week

64 (22)

− 0.03 (− 0.16 to 0.11)

0.7

− 0.09 (− 0.21 to 0.02)

0.1

Smoking history, n (%)

150 (49)

− 0.03 (− 0.09 to 0.14)

0.6

− 0.07 (− 0.17 to 0.03)

0.2

Transplant-specific characteristics

Dialysis before transplantation, n (%)

188 (61)

0.16 (0.05 to 0.27)

0.006

0.11 (0.01 to 0.21)

0.025

Living donor, n (%)

171 (55)

− 0.17 (− 0.29 to − 0.06)

0.002

− 0.08 (− 0.17 to 0.02)

0.1

Delayed graft functioning, n (%)

32 (11)

0.09 (-0.02 to 0.21)

0.1

0.03 (− 0.06 to 0.13)

0.5

Time after transplantation, years^†

4 [1 to 11]

0.07 (− 0.04 to 0.18)

0.2

0.04 (− 0.05 to 0.14)

0.4

History of rejection(s), n (%)

31 (10)

0.07 (− 0.05 to 0.18)

0.2

0.09 (− 0.01 to 0.19)

0.064

Postoperative CMV infection, n (%)

44 (15)

0.08 (− 0.03 to 0.20)

0.2

0.04 (− 0.06 to 0.14)

0.4

Patient reported outcome measurements

Feeling of anxiety, n (%)

68 (23)

0.01 (− 0.10 to 0.13)

0.8

0.06 (− 0.04 to 0.16)

0.2

Moderate to severe depressive symptoms, n (%)

15 (5)

− 0.10 (− 0.21 to 0.02)

0.097

− 0.05 (− 0.15 to 0.05)

0.3

Laboratory measurements

Hemoglobin, g/dL

13.5 ± 1.8

0.03 (− 0.14 to 0.09)

0.7

− 0.15 (− 0.25 to − 0.05)

0.004

Leukocyte count, 10⁹/L

7.5 ± 2.2

0.01 (− 0.10 to 0.13)

0.8

0.02 (− 0.07 to 0.12)

0.6

C-reactive protein, mg/L^‡

1.9 [0.7 to 4.1]

0.14 (0.03 to 0.25)

0.014

0.11 (0.01 to 0.21)

0.025

Plasma albumin, g/dL

4.3 ± 0.3

− 0.18 (− 0.29 to − 0.07)

0.002

− 0.11 (− 0.21 to − 0.01)

0.025

eGFR, mL/min/1.73m²

52 ± 17

− 0.11 (− 0.22 to 0.01)

0.064

− 0.07 (− 0.17 to 0.02)

0.1

Immunosuppressive drugs

Prednisolone, n (%)

300 (97)

0.11 (− 0.00 to 0.22)

0.06

0.08 (− 0.02 to 0.17)

0.1

Calcineurin inhibitor, n (%)

255 (83)

− 0.08 (− 0.19 to 0.04)

0.2

− 0.01 (− 0.11 to − 0.09)

0.9

Proliferation inhibitor, n (%)

267 (86)

− 0.07 (− 0.18 to 0.05)

0.2

− 0.06 (− 0.16 to 0.04)

0.2

mTOR inhibitor, n (%)

12 (4)

− 0.05 (− 0.17 to 0.06)

0.4

− 0.04 (− 0.14 to 0.05)

0.4