Figure 21 | Scientific Reports

Figure 21

From: The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1

Figure 21

ELK1 is the only highly expressed ETS genes in in-vitro derived human neurons and its expression cluster with CHD8 in human brain. (a) Average expression of ETS factors shows ELK1 is the only highly expressed ETS gene in differentiated human neurons (average FPKM values taken from wild type neurons). (b) Gene expression of CHD8 and ETS factor analysis in human developing cortex and unsupervised clustering of expression levels (Alan brain data)37.

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