Figure 2
From: Level of constitutively expressed BMAL1 affects the robustness of circadian oscillations
Constitutively expressed MYC-BMAL1 restores circadian rhythmicity in both PBmal1 and PPer2 activity. U2OS-PBmal1::Fluc/ΔBmal1/PTRE3Gs::Myc-Bmal1 strain-2 cells were transiently transfected with the PPer2::Eluc reporter and were treated with different concentrations of doxycycline (DOX). Dual wavelength luminescence measurements of PBmal1::Fluc and PPer2::Eluc were performed for 6 days. Data presented are the representative curves of 3 independent measurements. The orange lines show luminescence from PBmal1::Fluc and the green lines show luminescence of PPer2::Eluc.
