Figure 4 | Scientific Reports

Figure 4

From: Uterine epithelial Gp130 orchestrates hormone response and epithelial remodeling for successful embryo attachment in mice

Figure 4

Comprehensive gene expression analysis between control and Gp130 ecKO uteri before embryo implantation. (a) Volcano plot displaying differentially expressed genes whose expression levels were altered by a two-fold increase or decrease in Gp130 ecKO compared to the control (marked in red, FDR < 0.05). (b) Heatmap of differentially expressed genes. 338 genes are upregulated and 146 genes are down regulated in Gp130 ecKO. Heatmap was generated by the gplots v3.1.3 package in R v4.2.1 (URL https://www.R-project.org/). (c) Systematic characteristics of differentially expressed genes in Gp130 ecKO uteri compared to the control by GO analysis. BP biological process, CC cellular component, MF molecular function. (d) Selected significant pathway altered in Gp130 ecKO uteri.

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