Table 1 Background of women with BRCA pathogenic variants.

From: Impact of the coverage of risk-reducing salpingo-oophorectomy by the national insurance system for women with BRCA pathogenic variants in Japan

 

Total

Period A

Period B

p-value

BRCA1

BRCA2

BRCA1

BRCA2

BRCA pathogenic variant carriers

134

45

89

 < 0.001

27 (60%)

18 (40%)

47 (52.8%)

42 (47.2%)

0.54

Median age at RRSO (range)

48.5 (38–74)

50 (38–74)

48 (32–73)

0.12

Personal breast cancer history

122

39 (86.7%)

83 (93.3)

0.35

Familial history of OC within third degree

53

16 (35.6%)

33 (37.1%)

1

Parous

99

28 (62.2%)

71 (79.8%)

0.048

Paid by insurance

No

51

45 (100%)

6 (6.7%)

 < 0.01

Yes

83

0

83 (93.3%)

 

number per month

 

0

3.5

 < 0.01

  1. aRisk-reducing salpingo-oophorectomy.
  2. bBreast cancer.
  3. cOvarian cancer.