Figure 2 | Scientific Reports

Figure 2

From: Mapping the immune landscape in small cell lung cancer by analysing expression of immuno-modulators in tissue biopsies and paired blood samples

Figure 2

Immunohistochemical analysis of PD-L1, CTLA-4 and IDO1 in SCLC biopsies. (A,B) Immunostaining for IDO1 is seen in endothelial cells, intra-tumoral immune cells and stromal cells. (C) Immunostaining for CTLA-4 is seen in cytoplasm of tumor cells. (D) Strong membranous immunopositivity for PD-L1 is seen only in the tumor cells (TPS > 50%). (E) Histogram showing the intensity and percentage distribution of CTLA-4 immunoexpression in tumor cells amongst the SCLC cohort.

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