Table 1 Patient demographic information and histological evaluation of the lesional tissue.

From: Prognostic impact of lymphovascular and perineural invasion in squamous cell carcinoma of the tongue

 

P–V−

P–V + 

P + V−

P + V + 

Total

χ2

p-value

Gender

 Female

45 (35.4%)

4 (3.1%)

8 (6.3%)

2 (1.6%)

59 (46.5%)

0.517

0.915

 Male

50 (39.4%)

4 (3.1%)

10 (7.9%)

4 (3.1%)

68 (53.5%)

Age (years)

  < 60

52 (40.9%)

6 (4.7%)

10 (7.9%)

4 (3.1%)

72 (56.7%)

1.493

0.684

  ≥ 60

43 (33.9%)

2 (1.6%)

8 (6.3%)

2 (1.6%)

55 (43.3%)

Smoking

 No

73 (57.5%)

5 (3.9%)

13 (10.2%)

4 (3.1%)

95 (74.8%)

1.126

0.771

 Yes

22 (17.3%)

3 (2.4%)

5 (3.9%)

2 (1.6%)

32 (25.2%)

Alcohol

 No

74 (58.3%)

4 (3.1%)

15 (11.8%)

4 (3.1%)

97 (76.4%)

4.003

0.261

 Yes

21 (16.5%)

4 (3.1%)

3 (2.4%)

2 (1.6%)

30 (23.6%)

Pathologic T stage

 T1-2

81 (63.8%)

6 (4.7%)

10 (7.9%)

2 (1.6%)

99 (78%)

15.199

0.002*

 T3-4

14 (11%)

2 (1.6%)

8 (6.3%)

4 (3.1%)

28 (22%)

Pathologic N stage

 N0

78 (61.4%)

3 (2.4%)

12 (9.4%)

0 (0%)

93 (73.2%)

25.835

 < 0.001*

 N + 

17 (13.4%)

5 (3.9%)

6 (4.7%)

6 (4.7%)

34 (26.8%)

Tumor stage

 I-II

67 (52.8%)

3 (2.4%)

7 (5.5%)

0 (0%)

77 (60.6%)

18.495

 < 0.001*

 III-IV

28 (22%)

5 (3.9%)

11 (8.7%)

6 (4.7%)

50 (39.4%)

Histological grade

 Poorly-moderately

44 (34.6%)

7 (5.5%)

8 (6.3%)

4 (3.1%)

63 (49.6%)

5.897

0.117

 Well

51 (40.2%)

1 (0.8%)

10 (7.9%)

2 (1.6%)

64 (50.4%)

Postoperative radiotherapy

 No

83 (65.4%)

6 (4.7%)

12 (9.4%)

6 (4.7%)

107 (84.3%)

6.528

0.089

 Yes

12 (9.4%)

2 (1.6%)

6 (4.7%)

0 (0%)

20 (15.7%)

  1. P−V− PNI-negative with LVI-negative, P–V + PNI-negative with LVI-positive, P + V− PNI-positive with LVI-negative, P + V + PNI-positive with LVI-positive.
  2. *Statistically significant difference.