Figure 2
Transcutaneous NIRS, carotid blood pressure and spinal cord PO2 responses to pentobarbital administration. Averaged traces from (a) MAP (n = 7 animals, ± SEM), (b) spinal cord PO2, (n = 6, ± SEM), (c) TSI (%) (n = 8, ± SEM), and (d) relative changes in NIRS parameters of O2Hb, HHb, THb and Hbdiff (n = 8 ± SEM). The 5-min timepoint (dashed line) denotes the time of pentobarbital administration. (e,f) Delta changes to euthanasia relative to a 60-s pre-euthanasia baseline. TSI (%) tissue saturation index, Hbdiff hemoglobin difference, O2Hb oxygenated hemoglobin, HHb deoxygenated hemoglobin, THb total hemoglobin, MAP mean arterial pressure, PO2 partial pressure of oxygen, BSL baseline, EUT euthanasia.
