Figure 4
(A) Quantification of five miRNAs obtained from the serum extracellular vesicles of 44 patients for a validation study. G1 + 2 (LVI +) cohort has significantly lower miR-30d-5p levels (p = 0.036) than the G3 (LVI–) cohort. (B) miR-30d-5p levels in the healthy control group were significantly lower than those in the G2 (p = 0.022) and G3 (p = 0.047) cohorts. (C) miR-30d-5p levels in the healthy control group were significantly lower than those in the patients with lung adenocarcinoma (p < 0.001). (D) Recurrence-free survival curves of 27 patients with stage I lung adenocarcinoma according to their miR-30d-5p levels. EV extracellular vesicle.
