Figure 4
From: Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota
A deficiency of Axl reduced AMPs and increased proinflammatory cytokine expression. (a) mRNA expression of AMPs was analyzed by qRT-PCR in the colon of WT and Axl−/− mice. (b) Protein expression of cathelicidin was analyzed by western blot in the colon. (c) mRNA expression of inflammatory cytokines was analyzed by qRT-PCR in the colon and MLN. (d) Protein levels of IL-1β, IL-6 and IFN-γ were determined by ELISA in the colon and MLN. Data are shown as mean ± SEM. Significance (*p < 0.05, **p < 0.01, ***p < 0.001) was compared with WT mice and calculated by the Student's T-test.
